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    A Study from CCADD Cited in the British Guidelines for the Diagnosis and Management of Tumour Lysis Syndrome and a Review Article in the New England Journal of Medicine (NEJM).




    The research article entitled Prephase Steroid Treatment before Remission Induction Chemotherapy in Patients with Pediatric Acute Lymphoblastic Leukemia Using Common Data Model-Based Real-World Data: A Retrospective Observational Study1, which was first-authored by the former CCADD graduate,Yoona Choi, and co-authored by the members of CCADD  has been cited in the lastest haematology guidelines on the diagnosis and managemet of tumour lysis syndrome2 published by the British Society for Haematology. Moreover, the study was cited in a recent review article published in the New England Journal of Medicine (NEJM)3 detailing the epidemiology and pathophysiology of tumor lysis syndrome.


    The British Society for Haematology produces up-to-date evidence-based guidelines on the diagnosis and treatment of haematological disease, while The New England Journal of Medicine is one of the prominent journals of new medical knowledge and clinical best practicies worldwide (Impact Factor 78.5).


    This recognition highlights the clinical significance of our study in advancing evidence-based practice for pediatric acute lymphoblastic leukemia. CCADD takes pride in producing research that informs medical decision-making, and will continue efforts to deliver impactful studies.


    1_Choi Y, Kim BK, Won JH, Yoo JW, Choi W, Jung S, Kim JY, Choi IY, Chung NG, Lee JW, Choi JY, Kang HJ, Lee H. Prephase steroid treatment before remission induction chemotherapy in patients with pediatric acute lymphoblastic leukemia using common data model-based real-world data: a retrospective observational study. Clin Epidemiol. 2024 Apr 22;16:293-304. doi:10.2147/CLEP.S454263. PMID:38681782; PMCID:PMC11049150.

    2_Chan YLT, El-Sharkawi D, Shah P, Chanouzas D, O’Connor D, Marks SD, et al. British Society for Haematology updated guidelines for the diagnosis and management of tumour lysis syndrome in adults and children with haematological malignancies: a focus on patient safety. Br J Haematol. 2025;00:1-11. doi:10.1111/bjh.70092.

    3_Bociek RG, Lunning M. Tumor lysis syndrome. N Engl J Med. 2025 Sep 18;393(11):1104-1116. doi:10.1056/NEJMra2300923. PMID:40961427.

    By CCADD|September 30, 2025

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    CCADD

    Center for Convergence Approaches in Drug Development, Graduate School of Convergence Science and Technology, Seoul National University

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