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    [NEWS] The evolution of the regulatory agency
    [NEWS] How to design safe, scientific, efficient, and practical early phase clinical trials
    [NEWS] CCADD website is now official!
    [PUBLICATIONS]

    Lee HChung H, Lee S, Lee H, Yang SM, Yoon SH, Cho JY, Jang IJ, Yu KS. LBEC0101, A Proposed Etanercept Biosimilar: Pharmacokinetics, Immunogenicity, and Tolerability Profiles Compared with a Reference Biologic Product in Healthy Male Subjects. BioDrugs. 2017 May 27. doi: 10.1007/s40259-017-0230-9. [Epub ahead of print]

    [PUBLICATIONS]

    Yi S, Lee H, Jang SB, Byun HM, Yoon SH, Cho JY, Jang IJ, Yu KS. A novel K+ competitive acid blocker, YH4808, sustains inhibition of gastric acid secretion with a faster onset than esomeprazole: randomised clinical study in healthy volunteers. Aliment Pharmacol Ther. 2017 May 21. doi: 10.1111/apt.14148. [Epub ahead of print]

    [PUBLICATIONS]

    Oh J, Lee S, Lee H, Cho J-Y, Yoon SH, et al. The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans. PLoS one. 2017;12(4):e0176320.

    [PUBLICATIONS]

    Rhee SJ, Lee JW, Yu KS, Hong KT, Choi JY, Hong CR, Park KD, Shin HY, Song SH, Kang HJ, Lee H. Pediatric patients undergoing hematopoietic stem cell transplantation can greatly benefit from a novel once-daily intravenous busulfan dosing nomogram. American Journal of Hematology. 2017 Mar 28. doi: 10.1002/ajh.24734. [Epub ahead of print]

    [PUBLICATIONS]

    Kim A, Yu BY, Dueker SR, Shin KH, Kim HS, Ahn H, Cho JY, Yu KS, Jang IJ, Lee H. An accelerator mass spectrometry-enabled microtracer study to evaluate the first-pass effect on the absorption of YH4808. Clin Pharmacol Ther. 2017.2017 Feb 18 (Epub ahead of print)

    [PUBLICATIONS]

    Choi Y, Jiang F, An H, Park HJ, Choi JH, Lee H. A pharmacogenomic study on the pharmacokinetics of tacrolimus in healthy subjects using the DMETTM Plus platform. The Pharmacogenomics Journal. 2017;17(2):174-179

    [PUBLICATIONS]

    Lee HA, Lee S, Yim SV, Kim BH. Bioequivalence of two formulations of pregabalin 150-mg capsules under fasting conditions in healthy male subjects. International Journal of Clinical Pharmacology and Therapeutics. 2017 Feb, 55(2):171-176. doi: 10.5414/CP202698

    [PUBLICATIONS]

    Ju SM, Kim MS, Jo YS, Jeon YM, Bae JS, Pae HO, Jeon BH. Licorice and its active compound glycyrrhizic acid ameliorates cisplatin-induced nephrotoxicity through inactivation of p53 by scavenging ROS and overexpression of p21 in human renal proximal tubular epithelial cells. Eur Rev Med Pharmacol Sci. 2017 Feb. 21(4):890-899.

    [PUBLICATIONS]

    Lee H, Yim SV, Kim BH, Lee S. Comparative pharmacokinetic and bioequivalence evaluation of two formulations of morniflumate 350-mg tablets in healthy male subjects. Int J Clin Pharmacol Ther. 2017 Jan;55 (2017)(1):95-101.

    CCADD

    Center for Convergence Approaches in Drug Development, Graduate School of Convergence Science and Technology, Seoul National University

    Room C-208, 145 Gwanggyo-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16229, SOUTH KOREA (Gwanggyo)

    Room 406, Building 17, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul, SOUTH KOREA (Yeon-gun)

    Tel: +82-31-888-9189 (Gwanggyo); +82-2-3668-7381 (Yeon-gun)

    Fax: +82-31-888-9575

    Email: ccadd.snu@gmail.com