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    [PUBLICATIONS]

    Suh HY, Peck C, Yu K-S, Lee H. Determination of the starting dose in the first-in-human clinical trials with monoclonal antibodies: a systematic review of papers published between 1990 and 2013. Drug Des Devel Ther. 2016;Volume 10:4005-4016.

    [PUBLICATIONS]

    Kim A, Lim KS, Lee H, Chung H, Yoon SH, Yu KS, Cho JY, Jang IJ, Chung JY. A thorough QT study to evaluate the QTc prolongation potential of two neuropsychiatric drugs, quetiapine and escitalopram, in healthy volunteers. Int Clin Psychopharmacol. 2016;31(4):210-217.

    [PUBLICATIONS]

    Yoon S, Shin D, Lee H, Jang IJ, Yu KS. Pharmacokinetics, pharmacodynamics, and tolerability of LC350189, a novel xanthine oxidase inhibitor, in healthy subjects. Drug design, development and therapy. 2015;9:5033-5049.

    [PUBLICATIONS]

    Chung H, Lee H, Han H, et al. A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles. Drug design, development and therapy. 2015;9:2609-2616.

    [PUBLICATIONS]

    Oh J, Ji S, Lee H, Yu KS, Jang IJ. Response to "Induction of both P-glycoprotein and specific cytochrome P450 by Aspirin eventually does not alter the antithrombotic effect of clopidogrel". Clin. Pharmacol. Ther. 2015;97(4):325

    [PUBLICATIONS]

    Park SI, Lee H, Oh J, Lim KS, Jang IJ, Kim JA, Jung JH, Yu KS. A fixed-dose combination tablet of gemigliptin and metformin sustained release has comparable pharmacodynamic, pharmacokinetic, and tolerability profiles to separate tablets in healthy subjects. Drug design, development and therapy. 2015;9:729-736.

    [PUBLICATIONS]

    Lee H. Erratum to: Is Extrapolation of the Safety and Efficacy Data in One Indication to Another Appropriate for Biosimilars? AAPS J. 2015;17(6):1520-1521

    [PUBLICATIONS]

    Chung I, Yoon S, Yi S, Kim B-H, Yim S-V, Jang I-J, Lee H. A bioequivalence study of two levofloxacin tablets in healthy male subjects. Translational and Clinical Pharmacology. 2014;22(2):102.

    [PUBLICATIONS]

    Lee J, Lee H, Jang K, Lim KS, Shin D, KS Yu. Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan in healthy volunteers. Drug design, development and therapy, 2014 Oct 8;8:1781-8. doi: 10.2147/DDDT.S68574.

    [PUBLICATIONS]

    Lee J, Yoon S, Shin D, Han H, An H, Lee J, Lim KS, Yu KS, Lee H. Predictive performance of gentamicin dosing nomograms. Drug design, development and therapy. 2014;8:1097-1106.

    [PUBLICATIONS]

    Yi S, An H, Lee H, Lee S, Ieiri I, Lee Y, Cho JY, Hirota T, Fukae M, Yoshida K, Nagatsuka S, Kimura M, Irie S, Sugiyama Y, Shin DW, Lim KS, Chung JY, Yu KS, Jang IJ. Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment. Pharmacogenetics and genomics. 2014;24(10):477-485.

    [PUBLICATIONS]

    Jang K, Yoon S, Kim SE, Cho JY, Yoon SH, Lim KS, Yu KS, Jang IJ, Lee H. Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state. Drug design, development and therapy. 2014;8:851-858.

    CCADD

    Center for Convergence Approaches in Drug Development, Graduate School of Convergence Science and Technology, Seoul National University

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    Tel: +82-31-888-9189 (Gwanggyo); +82-2-3668-7381 (Yeon-gun)

    Fax: +82-31-888-9575

    Email: ccadd.snu@gmail.com